This quiz contains a mix of SL and HL questions
1. The diagram below shows rough sketch of a ribosome during translation.

ribosome, wikimedia commons

 DataBase Center for Life Science (DBCLS) CC BY 4.0

Which option is correct?

  Location where mRNA binds to initiate translation Location where tRNA binds to initiate translation Contains peptide bonds
A IV II III
B II I IV
C I I III
D I II IV

2. Which is the correct order for the process of transcription and the formation of mRNA?

I. RNA polymerase separates the DNA into two strands
II. RNA polymerase forms covalent bonds between the RNA nucleotides.
III. RNA nucleotides with complementary base pairing form along the antisense strand of DNA
IV. RNA polymerase binds to DNA at the site of a gene
  • A. I →  II → III → IV
  • B. II → I → IV → III
  • C. IV → I → III →  II
  • D. IV → II → III → I

Q3-5: Complete the sentences below about polypeptides:
Polypeptides are chains of joined together by condensation reactions.
During translation, on mRNA undergo
bonding with tRNA.
6. Which of the following is not a non-coding sequence of DNA?
  • A. Enhancer
  • B. Promoter
  • C. Telomeres
  • D. Exons
7. Which of the following is a post-transcriptional modification that occurs in eukaryotic cells?
  • A. Addition of 5' caps and 3' polyA tails to stabilize mRNA transcripts
  • B. Removal of exons and splicing together of introns to form mature mRNA
  • C. RNA polymerase producing a sequence of pre-mRNA
  • D. Addition of 3’ caps and 5’ polyA tails to stablize the mRNA transcripts
8. Which of these processes occurs first translation?
  • A. Large ribosome subunit binds mRNA
  • B. Small ribosome subunit binds mRNA
  • C. Initiator tRNA binds to AUG start codon
  • D. Initiator tRNA enters P site
9. Which statements are true for post-translational modification to create the hormone insulin?

I. Formation of a non-conjugated quaternary protein
II. Formation of disulfide bonds
III. Combining of four polypeptide chains
IV. Formation of pre-proinsulin from proinsulin
  • A. I and II only
  • B. II and III only
  • C. I and IV only
  • D. I, II, III, and IV
10. In Sickle Cell Disease the structure of haemoglobin is altered. Why does this occur?
  • A. Chromosomal trisomy altering the structure of haemoglobin
  • B. Point mutation altering the amino acid sequence in haemoglobin
  • C. pH changes altering the intermolecular forces in haemoglobin
  • D. Post-translational editing in the Golgi apparatus


Background Image by Tim Tim
CC-BY-SA 4.0